Editorial: Cell-Based Therapies for Diabetic Microvascular Complications
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منابع مشابه
Editorial: Cell-Based Therapies for Diabetic Microvascular Complications
There is an alarming increase in the number of cases of diabetes with the global prevalence rate at 9% for the year 2014 (1). Around 387 million patients worldwide are suffering from diabetes, and this number is expected to increase by 50% by 2030 (2). In particular, the South East Asian countries are affected most due to diabetes with projected 10% increase in diabetic patients by 2035 (3). Di...
متن کاملCell-Based Therapies for Diabetic Complications
In recent years, accumulating experimental evidence supports the notion that diabetic patients may greatly benefit from cell-based therapies, which include the use of adult stem and/or progenitor cells. In particular, mesenchymal stem cells and the circulating pool of endothelial progenitor cells have so far been the most studied populations of cells proposed for the treatment of vascular compl...
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The morbidity and mortality associated with diabetic complications impose a huge socioeconomic burden worldwide. Therefore, the ultimate goal of managing diabetes mellitus (DM) is to lower the risk of macrovascular complications and highly morbid microvascular complications such as diabetic nephropathy (DN) and diabetic retinopathy (DR). Potential benefits of incretin-based therapies such as gl...
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Microvascular complications characterized by retinopathy, nephropathy, and neuropathy are highly prevalent among diabetics. Glycemic control has long been the mainstay for preventing progression of these complications; however, such control is not easily achieved. Currently, alternative adjunctive approaches to treating and preventing microvascular damage are being undertaken by targeting the m...
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Intensive blood glucose control can prevent the initiation and progression of diabetic complications. However, the impacts of intensive therapy against diabetic complications might be limited, because of difficulty in maintaining blood glucose concentrations close to the normal range or other unknown reasons. Thus, another approach based on the elucidation of mechanisms of diabetic complication...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2015
ISSN: 1664-2392
DOI: 10.3389/fendo.2015.00146